Use of ENTONOX
Main clinical uses of ENTONOX
Nitrous oxide/oxygen medical gas mixture was first introduced in the UK in the 1960s as an analgesic agent for pain relief during labour. Since then, ENTONOX has become an excellent option in instances where a fast-acting potent analgesic with mild to moderate sedative effects is sought. Furthermore, it can be used safely in combination with other analgesic agents.
ENTONOX has a broad range of applications, from emergency medicine to painful diagnostic and therapeutic procedures. Common examples of its use are:
- Acute trauma such as fracture reduction and joint manipulation
- Short-term relief for treatments involving pain, such as wound and burns dressings, wound debridement (cleaning) and suturing
- Labour and childbirth
- Invasive procedures such as colonoscopies, lumbar puncture, cannulation and venepuncture
Use with other agents
ENTONOX can be used alone or in combination with other analgesic agents. The use of ENTONOX may allow reduction in the doses of the other agents such as morphine and pethidine, thus decreasing the potential side effects associated with them (1).
For information on ENTONOX in the treatment of children, please click here. Contraindications to the use of ENTONOX are listed here.
(1) Richebe P et al. Nitrous oxide revisited: evidence for potent antihyperalgesic properties. Anesthesiology 2005 Oct;103(4):845-854


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